4-Methylcinnamic Acid | CAS 1866-39-3 | C10H10O2

Other names: 4-Methylcinnamic aldehyde; (2E)-3-(4-Methylphenyl)-2-propenoic acid; 2-Propenoic acid, 3-(4-methylphenyl)-; Cinnamic acid, p-methyl-; AKOS BBS-00007857; AKOS BBB/231; METHYLCINNAMIC ACID,4-TRANS; 4-METHYLCINNAMIC ACID

CAS No.: 1866-39-3

Molecular formula: C10H10O2

Molecular weight: 161.178

Molar mass: 161.178 g/mol

Melting point: 198-201°C

Boiling point: 228.88°C (rough estimate)

Flash point : 206.1°C

Refractive index : 1.5766

Properties: White Crystalline Powder

Purity: 99%

Packaging: 25kg

Storage method: Store below 30°C

It is used to synthesize methyl p-methyl cinnamate. Methyl p-methyl cinnamate is mainly used to synthesize p-bromomethyl cinnamate as the upstream raw material of the antithrombotic drug Ozagrel sodium. P-bromomethylcinnamate is brominated with N-bromosuccinimide to produce p-bromomethylcinnamate. Methyl p-bromomethylcinnamate is in ionic liquid N-n-butylpyridine tetrafluoroborate. After condensing with imidazole at room temperature in the acid salt, alkaline hydrolysis was performed to obtain the antithrombotic drug ozagrel sodium, with a total yield of 67%.